VOLATILE ORGANIC COMPOUNDS IN PHARMACEUTICAL PRODUCTS AND BIOLOGICAL MATERIALS

This web page deals with a method for the analysis of volatile organic compounds in solid or liquid materials. It comprises techniques for screening for such substances, as well as their identification and quantification, and has been shown to be a tool in the survey of suspected intoxication, arson, or drug copy.

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CONTENTS

Practical utility of testing volatiles Survey of solvent or gas intoxication Arson analysis Survey of suspected drug copy Analytical methods Apparatus set up Extracting volatiles Search for volatiles Identification of volatiles Quantitation of volatiles Scientific references

Some "real life" applications of methods What agent caused the intoxication death ? Was the over-the-counter drug a copy or original ? Reconstructed chromatogram Drug "signature " and conclusion Was it an accidental fire or arson that killed Jim? Reconstructed chromatogram and conclusion Summary of curriculum vitæ Aim of web page

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Jan Schuberth, M.D., Ph.D Oxeltunet 1, SE-181 48, Sweden telephone/fax: +46 (0)8 765 84 65

Copyright © 1996, Jan Schuberth revised 29 November 2003